Bufo Divine Union Medicine

The Medicine

Bufo, also known as Sapito, is the psychoactive substance derived from the venomous secretions of the Sonoran Desert toad (Bufo alvarius). Its use has a history in some indigenous Mesoamerican cultures where it has been used in shamanic and healing practices. Close up of a Bufo alvarius, the frog that produces Bufo. The ceremonial method of using Bufo alvarius secretions involves drying the toad's venom and then vaporizing it. The vapor is typically inhaled for a short duration to induce intense and transformative psychedelic experiences. Although the secretions are toxic if ingested, they are non-toxic when vaporized and inhaled, as the toxins are heat sensitive and destroyed during the vaporization process. The substance secreted by the toads contain a potent natural psychoactive compound known as 5-MeO-DMT (5-Methoxy-N,N-Dimethyltryptamine), which is heat stable and is the primary psychoactive compound in this medicine.

The Experience

The Bufo experience is short but incredibly powerful. Because the medicine is inhaled as smoke from a pipe, the onset is almost immediate, and the experience typically lasts from 10-20 minutes. The experience itself is one that those who have experienced it often cannot put words around. It is typically a deeply spiritual rather than visual experience. It is common to experience a profound dissolution of the ego in a way that some describe as meeting their higher self or the "god" version of themselves. Those who surrender themselves to the experience can come away having received deep healing, with profound shifts in their physical and psychological state.